(767) 448- 0100 / 440- 4583
Home Office: 24 Cross St, Roseau, Dominica
Leptospirosis IgM/IgG Screen Test
Leptospirosis IgM/IgG Screen Test
7th Dec


Leptospirosis occurs worldwide and is a common mild to severe health problem for humans and animals, particularly in areas with a hot and humid climate. The natural reservoirs for leptospirosis are rodents as well as a large variety of domesticated mammals.

Health Advisory Leptospirosis

Human infection is caused by Leptospira interrogans, the pathogenic member of the genus of Leptospira.   The infection is spread via urine from the host animal; hence human infection is through ingestion of urine-contaminated water and food.

After infection, leptospires are present in the blood until they are cleared after 4 – 7 days following the production of anti-leptospira interrogans antibodies, initially of the IgM class, followed by the IgG class.  After 7 days, the bacteria can be found in fresh urine.

Leptospirosis infection in humans causes a wide range of symptoms, and some infected persons may have no symptoms at all. Leptospirosis is a biphasic disease that begins suddenly with fever, accompanied by chills, intense headache, severe muscle ache, abdominal pain, vomiting, diarrhoea, red eye, and occasionally a skin rash.

There are 2 phases of the infection:

  1. Acute or Septicemic phase – this is the incubation phase when symptoms mimic that of common viral infections such as
    dengue and the flu; but some persons may be asymptomatic.
  2. Chronic or Weil’s disease – this is characterized by liver damage (causing jaundice), kidney failure, and bleeding.  Additionally,
    the heart, lung and brain can be affected (meningitis and encephalitis).

We are proud to announce our latest test, the Leptospira IgM/IgG screen test.  The test is a qualitative serology screen for the detection of Leptospira IgM/IgG antibodies in human serum or plasma.  For more information, please call the laboratory.